Chromosomes,+genes,+alleles+and+mutations

4.1.1 State that eukaryote chromosomes are made of DNA and proteins.

4.1.2 Define //gene //, //allele //and //genome //.

4.1.3 Define //gene mutation //.

4.1.4 Explain the consequence of a base substitution mutation in relation to the processes of transcription and translation, using the example of sickle-cell anemia.